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10.1016/j.jare.2018.06.005 J Adv Res

1 Introduction Malignant melanotic nerve sheath tumors (MMNSTs), previously referred to as melanotic schwannomas (MS), are exceptionally rare neoplasms accounting for less than 1% of primary peripheral nerve sheath tumors ( For localized MMNST, treatment typically involves surgical resection (gross-total resection [GTR] or subtotal resection [STR]) combined with adjuvant radiotherapy ( VEGFR1/2/3 , c-Kit , PDGFR- , and FGFR , thereby disrupting tumor growth and survival signaling pathways ( 2 Case description A 54-year-old female presented with a right neck mass without other associated symptoms

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In brief, the presence of Schwannian whorls, a peritumoral capsule, subcapsular lymphocytes, macrophage-rich infiltrates, and an absence of fascicles favor the diagnosis of cellular schwannoma ( P 0.05 for all)

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